You are correct in the regard that we cannot observe, recreate, or somehow "prove" any concept of abiogenesis. What we can do, however, is develop hypotheses and test some aspects of their validity to give us a framework to go with. Even if these are not provable, I feel that they have more validity than a supernatural creation hypothesis.
It is a "god of the gaps" scenario where we shouldn't give equal or greater weight to a supernatural origin of life than a natural origin just because we have not discovered the answer yet (if we ever do). Humanity ascribed the supernatural to everything that they didn't understand (the gaps) and that amount has slowly dwindled as we acquire a better understanding of the natural world around us. There is no reason to not assume there is a natural explanation for genesis just because we haven't found one yet.
Imagine you are eating at a cafeteria every morning for a year. You get up on time 355 days out of the year and each day they serve waffles. Nothing else, just waffles. Just because you slept in and didn't find out what they served for the other 10 days, there is no reason to assume that it was pancakes. The safe bet is waffles, just like the safe bet for genesis is a natural origin.
As for the origin of the universe... obviously we have no real answer, but I'd bet again on the natural origin (although probably a natural origin beyond our current comprehension).