My initial gut response is: what would the Lord have to return to?
Scripture makes it clear that the destructive plagues just prior to His return, and His return Himself will be at His hands.
People try to see helicopters in Rev 9, but I prefer to take things as written, and so there will be such creatures rising from the bottomless pit on earth.
And the same hour was there a great earthquake, and the tenth part of the city fell, and in the earthquake were slain of men seven thousand: and the remnant were affrighted, and gave glory to the God of heaven.
These things in Revelation will be done by God, as with Egypt, in the way to show it can only be God doing such things, which is not warfare of man.
So, I don't believe God will allow man to destroy himself on earth. Like the flood, if anyone is going to do that, it will be God Himself: God is omnipotent and only allows things to happen according to His own will.
But nevertheless, for the saints in Christ Jesus, a nuke on the head would be a perfect way to go to heaven with no fuss nor muss.