No. For example, it's clear enough from the Bible that we are descended from two people. We know it's difficult to maintain a population from a single pair over time. Usually, if a species declines to a few hundred individuals, it's doomed. But not always. So if one took science above scripture, one would doubt the actual existence of two people as founders.
But that wasn't my point. My point is scripture rarely makes scientific claims; Genesis, as I said, isn't about how any of the biology went down. It's about God and His creation with regard to man and our relationship.
If you accept scripture as it is, there is no "fence." This is a whole, with no conflicts, because Genesis isn't even talking about the mechanics of creation. This is why we have difficulty. You see it as some kind of dichotomy, when it is nothing of the kind. As Pope John Paul II remarked about the issue, truth cannot contradict truth. But as St. Augustine wrote, we can be wrong about anything, and if we believe something that later is clearly refuted by evidence, we should be humble enough to acknowledge our imperfection and learn from it.
Once you get that, the "fence" goes away. God is truth. Christians should never fear the truth.