It likely means that Paul received some incredible revelations and so to keep him from becoming conceited, he was given some sort of "thorn in the flesh" to keep him humble. What of it?
I don't want to take this off topic discussing Paul's thorn in the flesh, but to only show what it was as being the same thorn in our flesh that will try to buffet us at times.
Paul's thorn in the flesh was that of Satan's messenger trying to buffet him. Buffet here means to strike repeatedly as Satan used his demons to come against Paul and persecute him everywhere he went. Paul prayed three times for God to take these persecutions away and God said no as God said "My grace is sufficient for thee: for my strength is made perfect in weakness".
God is not going to keep us from being persecuted as even His own Son Christ Jesus was persecuted to death on the cross and many martyrs after him in other ways, even so still today as many are persecuted even to death for the witness of Christ. God gives us His power and authority through His grace to give us strength when we are persecuted like Paul said:
2Corinthians 12:9 Most gladly therefore will I rather glory in my infirmities, that the power of Christ may rest upon me.
2Corinthians 12:10 Therefore I take pleasure in infirmities, in reproaches, in necessities, in persecutions, in distresses for Christ's sake: for when I am weak, then am I strong.
Act 9:15; 2 Corinthians 4:8-12; Galatians 5:11; 2 Timothy3:10, 11; 1 Corinthians 15:30-32; 2 Corinthians 4:7-18; 6:3-10; 11:23-28; 12:5-10; Galatians 4:13, 15
2Co 6:3 Giving no offence in any thing, that the ministry be not blamed:
2Co 6:4 But in all things approving ourselves as the ministers of God, in much patience, in afflictions, in necessities, in distresses,
2Co 6:5 In stripes, in imprisonments, in tumults, in labours, in watchings, in fastings;
2Co 6:6 By pureness, by knowledge, by longsuffering, by kindness, by the Holy Ghost, by love unfeigned,
2Co 6:7 By the word of truth, by the power of God, by the armour of righteousness on the right hand and on the left,
2Co 6:8 By honour and dishonour, by evil report and good report: as deceivers, and yet true;
2Co 6:9 As unknown, and yet well known; as dying, and, behold, we live; as chastened, and not killed;
2Co 6:10 As sorrowful, yet alway rejoicing; as poor, yet making many rich; as having nothing, and yet possessing all things.