I guess it just depends on your definition of "God's presence".Genesis 3:20-23 And Adam called his wife's name Eve, because she was the mother of all living. Also for Adam and his wife the Lord God made tunics of skin, and clothed them. Then the Lord God said, "Behold, the man has become like one of Us, to know good and evil. And now, lest he put out his hand and take also of the tree of life, and eat, and live forever"--therefore the Lord God sent him out of the garden of Eden to till the ground from which he was taken.
Dave
As God was still talking with men when Cain and Abel did their sacrifices, I find it difficult to think He wasn't somehow present with Adam and Eve anymore.