I'm more thinking of the whole "repercussions on humanity" because as far as I can see, nowhere in the Genesis text does it say every person throughout history will be affected by this one act.
We all die physically but I think we were always designed to;
Genesis 3:22 NIV
And the Lord God said, "The man has now become like one of us, knowing good and evil. He must not be allowed to reach out his hand and take also from the tree of life and eat, and live forever."
I agree that the death referred to when it says Adam and Eve is a spiritual one in terms of seperation from God but again, it doesn't say anything about it impacting all of human history.
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God did not create death. Actually death is the loss of life. God created man to live forever, eternally with Him, in union with Him. But He also wanted that union to be freely entered into, by man's desire.
It would be quite absurd that God then would create man to be annihilated, return to dust from whence he came, if eternity is the end result.
As to effect upon all history. Gen 3:19 is the sentence upon Adam, but then Able is killed, so we now know that death is in this world. Paul is probably the first to show that death, the physical loss of life came through Adam in Rom 5:12. The solution being life to all men in vs 18. Rom 11:32 also shows that God allowed Satan to have dominion over man through the power of death. This is stated as being the cause of Christ to come, Heb 2:14. Another equation of I Cor 15:22 states quite emphatically that death came to all men through Adam, and then that life to all men came through Christ. Vs 22 is a summary of the explanation of what kind of death Paul is actually speaking about, vs 19-21.
If death was only spiritual then there surely would be no need to redeem the world, the universe either, since it cannot sin. But we know Christ redeemed the world, Col 1:20, II Cor 5:18-19 and is called the Savior of the world, John 4:42.
John even confirms this is John 6:39 where all things that were given to Christ, (all things of Col 1:20) none would be lost and all would be raised in the last day.
Just to give you the contrast, vs39 is about believers. Of all those human beings in vs 40 that were given life, physical eternal existance again) who see and believe will be raised to be with Christ. Which is supported by Acts 24:15, Rev 20:12-13.
We also know that Christ's birth, life, death and resurrection was all physical. Nothing about it was a spiritual event to overcome a spiritual death, which is a relational event or occurance.
It is Christ overcoming physical death that makes the relational possible. It is the ONLY reason man needed Christ. A mortal man, a dead man or a man living in a state of death could not surely given himself eternal life, a physcial eternal existance. Having a relationship does not grant physical life either. We know that a physical life only comes as a result of Christ's resurrection, and we will all (mankind) be raised, I Cor 15:53 and be made eternal, immortal and incorruptible.
To actually hold to the concept of Original Sin, one would need to reconstruct most of scripture to shore it up.